VITAMIN C - The most advanced technology to stabilize antioxidants

BIOMIMETISM - ALPHASCIENCE INSPIRED BY NATURE TO STABILIZE ANTIOXIDANTS

20 Sep 2023

PHYTIC [TC] SERUM: A UNIQUE AND STABLE MOLECULAR COMBINATION

8% L-ASCORBIC ACID (vitamin C in its natural form)

Skin surface: boosts epidermical cells turnover to enhance skin radiance and refine skin texture.
At dermis level: significantly increases collagen and dermis component synthesis (1,2,3) to reduce wrinkles and improve skin structure.
One of the most powerful antioxidants to protect skin cells against external agressions (UV, stress, pollution,...). This makes L-Ascorbic Acid a must-have to prevent skin aging.
Anti-spot activity thanks to its antioxidant action and limitation of melanin transfer by the weakening of dendrites (4).

2% PHYTIC ACID

Powerful antioxydant and anti-cancer (5)
Anti pollution (chelates iron and scavengers heavy metals)
Regulates pigmentation and normalises skin sebum rate (6)
Synergistic stabilization action with L-ascorbic acid.

0,2% TANNIC ACID

Powerful antioxidant, neutralises pro-oxydative Fenton reaction (7)
Chelates iron and anti-pollution effect
Stimulates collagen synthesis

COMPARATIVE TECHNIQUES TO STABILIZE L-ASCORBIC ACID (VITAMIN C)

L-ascorbic acid (vitamin C in its natural form) is highly unstable in contact with air and water oxygen, especially with warm temperature.
Different techniques are used to stabilize it with unequal results.

	ADVANTAGES	DISADVANTAGES
ALPHASCIENCE TECHNOLOGY BIOMIMETISM - INSPIRED BY NATURE Molecular combination of L-ascorbic acid with powerful antioxidants.	Excellent stability in the skin and with heat. Efficiency and bioavailability.	Complex formulas
Encapsulated L-ascorbic acid	Easy to formulate	Limited to medium concentrations (3 to 4%). Low stability.
Vitamin C derivatives (ascorbosilane, sodium ascorbyl phosphate, etc)	Easy to formulate	Low anti-aging and antioxidant efficiency.
Dry form of L-ascorbic acid (powder) to mix with a solution before use.	Easy to formulate. Stable before mixing.	No guarantee of stability after mixing. Weak penetration. Uneasy for patient.

BIOMIMETISM: ALPHASCIENCE IS INSPIRED BY NATURE TO STABILIZE ANTIOXIDANTS

How do fruits which contain a lot of water manage to keep their vitamin C and antioxidants content stable and active?

L-ascorbic acid (vitamin C in its natural form) is fully stable in an orange for example, because it is associated with other antioxidants such as polyphenols and flavonoids.
This assemblage forms a complex chemical structure that is totally stable dynamically.

ALPHASCIENCE STABLE MOLECULAR COMBINATION

By observing nature and thanks to our control of the chemical interactions between antioxidants and Vitamin C, we developed a unique associative complex of powerful antioxidants which ensures the stabilization of highly concentrated L-ascorbic acid.

FOR THE 1ST TIME: STABILIZATION EVIDENCE AT HIGH TEMPERATURE

Evolution of L-Ascorbic Acid concentration in Alphascience serum
HPLC mesures by an indépendant laboratory (SGS Multilab)

Bibliography:

Nusgens BV, Humbert P, Rougier A, et al. Topically applied vitamin C enhances the mRNA level of collagens I and III, their proces- sing enzymes and tissue inhibitor of matrix metalloproteinase 1 in the human dermis J Invest Dermatol 2001; 116 : 853-859
Stimulation of collagen gene expression by ascorbic acid in cultured human fibroblasts. A role for lipid peroxidation? M Chojkier, K Houglum, J Solis-Herruzo and D A Brenner
Ascorbic acid enhances the expression of type 1 and type 4 collagen and SVCT2 in cultured human skin fibroblasts. Y Kishimoto, N Saito, K Kurita, K Shimokado
Marta I. Rendon MD, Jorge I. Gaviria MD - Review of Skin-Lightening Agents - Dermatologic Surgery
Crit Rev Food Sci Nutr. 1995 Nov;35(6):495-508. Phytic acid in health and disease. Zhou JR1, Erdman JW Jr.
Dr Zhong, Soongsil University
Polyphenol tannic acid inhibits hydroxyl radical formation from Fenton reaction by complexing ferrous ions. George K.B. Lopes, Herbert M. Schulman, Marcelo Hermes-Lima